午夜插插,噜噜噜影院,啪啪伊人网,欧美熟夫,景甜吻戏视频,男人强操性感蕾丝美女视频在线网站,日本美女跳舞视频

ChemicalBook--->CAS DataBase List--->117354-64-0

117354-64-0

117354-64-0 Structure

117354-64-0 Structure
IdentificationBack Directory
[Name]

2-HYDROXYSACLOFEN
[CAS]

117354-64-0
[Synonyms]

2-Oh-saclofen
HYDROXYSACLOFEN
2-HYDROXYSACLOFEN
2-Hydroxysaclofen solid
2-HYDROXYSACLOFEN, >99%
2-Hydroxysaclofen >=98% (TLC), solid
2-HYDROXYSACLOFEN ISO 9001:2015 REACH
2-HYDROXYSACLOFEN GABA(B) RECEPTOR ANTA
3-amino-2-(4-chlorophenyl)-2-hydroxy-*propanesulf
3-AMINO-2-(4-CHLOROPHENYL)-2-HYDROXY-PRO PANESULFON
3-AMINO-2-(4-CHLOROPHENYL)-2-HYDROXYPROPANE-SULFONIC ACID
3-amino-2-(4-chlorophenyl)-2-hydroxypropane-1-sulfonicaci
3-Amino-2-(4-chlorophenyl)-2-hydroxypropane-1-sulfonic acid
3-Amino-2-hydroxy-2-(4-chlorophenyl)propane-1-sulfonic acid
(+/-)-3-AMINO-2-(4-CHLOROPHENYL)-2-HYDROXYPROPYLSULFONIC ACID
(RS)-3-AMINO-2-(4-CHLOROPHENYL)-2-HYDROXYPROPYL-SULFONIC ACID
(RS)-3-AMINO-2-(4-CHLOROPHENYL)-2-HYDROXYPROPANESULPHONIC ACID
(+/-)-3-AMINO-2-(4-CHLOROPHENYL)-2-HYDROXY-PROPANESULFONIC ACID
Benzeneethanesulfonic acid, β-(aminomethyl)-4-chloro-β-hydroxy-
beta-(Aminomethyl)-4-chloro-beta-hydroxybenzeneethanesulfonic acid
Benzeneethanesulfonic acid, beta-(aminomethyl)-4-chloro-beta-hydroxy-
[Molecular Formula]

C9H12ClNO4S
[MDL Number]

MFCD00069282
[MOL File]

117354-64-0.mol
[Molecular Weight]

265.71
Chemical PropertiesBack Directory
[Melting point ]

267-269 °C
[RTECS ]

DA0359200
[storage temp. ]

2-8°C
[solubility ]

H2O: 1 mg/mL
[form ]

solid
[color ]

white
[Water Solubility ]

Soluble in water at 1mg/ml. Also soluble in DMSO, 0.1M HCl and methanol
Safety DataBack Directory
[Hazard Codes ]

C
[Risk Statements ]

34
[Safety Statements ]

26-27-36/37/39-45
[RIDADR ]

UN 1759 8/PG 3
[WGK Germany ]

3
[HazardClass ]

8
Hazard InformationBack Directory
[Uses]

2-Hydroxysaclofen is a GABA-B receptor antagonist in the ventral tegmental area and may play a role in the mechanisms of cocaine usage. Affects specific acute nicotine responses in mice, abolishing hypolocomotion and increasing antinociception.
[Definition]

ChEBI:3-amino-2-(4-chlorophenyl)-2-hydroxy-1-propanesulfonic acid is an organochlorine compound.
[Biological Activity]

Selective antagonist at GABA B receptors.
[in vivo]

2-Hydroxysaclofen (0.25-1 mg/kg; IP; single dosage) abolishes nicotine hypolocomotor effects and increases the antinociceptive effects of nicotine[1].
2-Hydroxysaclofen (0.3-3 mg/kg; IP; single dosage) reduces the effects of Baclofen (a GABA receptor agonist) on d-amphetamine-induced discriminative cue[2].
2-Hydroxysaclofen (0-100 μg/2 μl; ICV; single dosage) produces a rapid elevation in the serum LH concentration in the estrogen-primed ovariectomized rat[3].

Animal Model:Male Swiss Webster mice (22-24 g; treated with 3 mg/kg nicotine)[1]
Dosage:0.25, 0.5 and 1 mg/kg
Administration:IP; single dosage; after 10 or 45 min of nicotine administration
Result:Abolished nicotine hypolocomotor effects at 1 mg/kg, and increased the antinociceptive effects of nicotine at 1 mg/kg.
Animal Model:Male Wistar rats[2]
Dosage:0.3, 1 and 3 mg/kg
Administration:IP; single dosage
Result:Reduced the effects of Baclofen on d-amphetamine-induced discriminative cue.
Animal Model:Female Wistar rats (8 weeks)[3]
Dosage:0, 20, 50 or 100 μg/2 μL
Administration:ICV; single dosage
Result:Produced a rapid elevation in the serum LH concentration in the estrogen-primed ovariectomized rat with a dose-dependent manner, and the peak LH values were observed 10 min after the injection.
The effect was dose-dependent, as 0 or 20 μg of the antagonist was ineffective while a pronounced effect was observed after the injection of 50 or 100 μg.
[storage]

Store at RT
117354-64-0 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000 , +1-00000000000
Website: https://www.targetmol.com/
Company Name: Dideu Industries Group Limited
Tel: +86-29-89586680 +86-15129568250 , +86-15129568250
Website: https://www.dideu.com
Company Name: Hangzhou MolCore BioPharmatech Co.,Ltd.
Tel: +86-057181025280; +8617767106207 , +8617767106207
Website: https://www.molcore.com/
Company Name: DAYANG CHEM (HANGZHOU) CO.,LTD
Tel: +86-88938639 +86-17705817739 , +86-17705817739
Website: www.dycnchem.com
Company Name: J & K SCIENTIFIC LTD.  
Tel: 18210857532
Website: www.jkchemical.com
Company Name:   
Tel: 821-50328103-801 18930552037
Website: http://www.yuhua99.com/ShowSupplierProductsList13285/0.htm
Company Name: Guangzhou Isun Pharmaceutical Co., Ltd  
Tel: 020-39119399 18927568969
Website: http://www.isunpharm.com
Company Name: AdooQ BioScience, LLC   
Tel: +1 (866) 930-6790
Website: www.adooq.com
Company Name: BOC Sciences  
Tel:
Website: https://www.bocsci.com
Company Name: Energy Chemical  
Tel: 021-58432009 400-005-6266
Website: http://www.energy-chemical.com
Company Name: MedBioPharmaceutical Technology Inc  
Tel: 021-69568360 18916172912
Website: http://www.med-bio.cn/
Company Name: TargetMol Chemicals Inc.  
Tel: 4008200310
Website: https://www.targetmol.cn/
Company Name: Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd  
Tel: 024-024-024-88590548 18341751992
Website:
Company Name: Wuhan Jingkangen Biomedical Technology Co., Ltd  
Tel: 13720134139 086-15871494362 13720134139
Website: https://www.jknbiochem.com
Company Name: Nantong QuanYi Biotechnology Co., Ltd  
Tel: 0513-66337626 18051384581
Website: https://www.chemhifuture.com/
Company Name: Baoji Didu Pharmaceutical and Chemical Co., Ltd  
Tel: 029-02961856358 15829236573
Website:
Company Name: Shaanxi Gulliver Biotechnology Research Co., Ltd  
Tel: 0917-7795337 18409274651
Website:
Company Name: R&D Systems, Inc  
Tel: 18003437475 18003437475
Website: www.rndsystems.com
Tags:117354-64-0 Related Product Information
125464-42-8 57267-78-4

  • HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
  • All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
    According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.
  • Copyright © 2023 ChemicalBook All rights reserved.