Identification | Back Directory | [Name]
Benzamide, 3-[5-[(2-fluorophenyl)amino]-1H-indazol-1-yl]-N-(3,4,5-trimethoxyphenyl)- | [CAS]
1164153-37-0 | [Synonyms]
SR3737 SR-3737 SR 3737 Benzamide, 3-[5-[(2-fluorophenyl)amino]-1H-indazol-1-yl]-N-(3,4,5-trimethoxyphenyl)- | [Molecular Formula]
C29H25FN4O4 | [MOL File]
1164153-37-0.mol | [Molecular Weight]
512.53 |
Hazard Information | Back Directory | [Description]
SR-3737 is a potent inhibitor of both JNK3 and p38. | [Uses]
SR-3737 is a JNK3 and p38 inhibitor (IC50: 12 and 3 nM)[1]. | [References]
[1] Kamenecka T, et al. Structure-activity relationships and X-ray structures describing the selectivity of aminopyrazole inhibitors for c-Jun N-terminal kinase 3 (JNK3) over p38. J Biol Chem. 2009 May 8;284(19):12853-61. DOI:10.1074/jbc.M809430200 |
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