| Identification | Back Directory | [Name]
PD 123177 | [CAS]
114785-12-5 | [Synonyms]
XD-329
EXP-655
PD 123177
2,3-dihydro-1h-iMidazo[4,5-c]pyridine-7-carboxylicacid
1-[(4-Amino-3-methylphenyl)methyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid | [Molecular Formula]
C29H28N4O3 | [MOL File]
114785-12-5.mol | [Molecular Weight]
480.56 |
| Hazard Information | Back Directory | [Description]
PD 123177 is a Nonpeptide angiotensin AII-2 inhibitor. | [Uses]
PD 123177 is a nonpeptide antagonist specific for angiotensin II (AII) subtype AT2 receptor in mammalian systems[1]. | [Definition]
ChEBI: PD 123177 is a diarylmethane. | [IC 50]
AT2 Receptor | [References]
[1] C S Cobb, et al. Characterization of putative glomerular receptors for angiotensin II in the rainbow trout Oncorhynchus mykiss using the antagonists Losartan, PD 123177, and saralasin. Gen Comp Endocrinol. 1993 Oct;92(1):123-31. DOI:10.1006/gcen.1993.1149 |
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