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ChemicalBook--->CAS DataBase List--->1146-98-1

1146-98-1

1146-98-1 Structure

1146-98-1 Structure
IdentificationBack Directory
[Name]

Bromindione
[CAS]

1146-98-1
[Synonyms]

HL 255
Fluidane
Halinone
Circladin
FluideMin
FluideMol
Haldinone
M.G. 2555
Bromindione
BroMophendione
BroMophenindione
2-(p-BroMophenyl)-1,3-indandione
2-(4-BROMOPHENYL)-1,3-INDANDIONE
2-(4-bromophenyl)indene-1,3-dione
2-(4-bromophenyl)indane-1,3-quinone
2-(4-Bromophenyl)-1H-indene-1,3(2H)-dione
1H-Indene-1,3(2H)-dione, 2-(4-bromophenyl)-
2-(4-Bromophenyl)-2,3-dihydro-1H-indene-1,3-dione
[Molecular Formula]

C15H9BrO2
[MDL Number]

MFCD00087378
[MOL File]

1146-98-1.mol
[Molecular Weight]

301.13
Chemical PropertiesBack Directory
[Melting point ]

139-142°C
[density ]

1.4993 (rough estimate)
[refractive index ]

1.4650 (estimate)
[storage temp. ]

Amber Vial, -20°C Freezer
[solubility ]

Chloroform, Methanol
[form ]

Solid
[color ]

Black
[Stability:]

Light Sensitive
Safety DataBack Directory
[RIDADR ]

2811
[HazardClass ]

6.1(b)
[PackingGroup ]

III
[HS Code ]

2914199090
[Toxicity]

LD50 oral in mouse: 200mg/kg
Hazard InformationBack Directory
[Chemical Properties]

Black Solid
[Originator]

Bromindione,Chemical Formulations
[Uses]

Anticoagulant.
[Uses]

antidiabetic
[Definition]

ChEBI: Bromindione is a member of indanones and a cyclic ketone.
[Manufacturing Process]

To a solution of 1.85 g of sodium in 40 ml of ethanol, was added 10 g of phthalide and 14.0 g of p-bromobenzaldehyde, and the reaction mixture was heated on the steam bath for one hour. Water was then added, and the alcohol was distilled off. Then after adding additional water, the reaction mixture was acidified with hydrochloric acid to precipitate the crude product, which was filtered off, dried and recrystallized from methanol. The 2-pbromophenylindandione is in the form of dark red crystals, having a melting point of 133-135°C.
[Therapeutic Function]

Anticoagulant
[storage]

Store at -20°C
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