| Identification | Back Directory | [Name]
BOC-L-PYROGLUTAMIC ACID BENZYL ESTER | [CAS]
113400-36-5 | [Synonyms]
PYR294
Boc-Pyr-Obzl
(Tert-Butoxy)Carbonyl Pyr-OBzl
Boc-PyroglutaMic acid. Benzyl ester
BOC-L-PYROGLUTAMIC ACID BENZYL ESTER
(2S)-benzyl N-(tert-butyloxycarbonyl)-pyroglutamate
Benzyl (S)-1-Boc-5-oxopyrrolidine-2-carboxylate, 98%
(S)-2-Benzyl 1-tert-butyl 5-oxopyrrolidine-1,2-dicarboxylate
2-benzyl1-(tert-butyl)(S)-5-oxopyrrolidine-1,2-dicarboxylate
2-benzyl 1-tert-butyl (2S)-5-oxopyrrolidine-1,2-dicarboxylate
2-O-benzyl 1-O-tert-butyl (2S)-5-oxopyrrolidine-1,2-dicarboxylate
(2R)-5-Oxo-1,2-pyrrolidinedicarboxylic acid 1-(tert-butyl) 2-(phenylmethyl) ester
1,2-Pyrrolidinedicarboxylic acid, 5-oxo-, 1-(1,1-diMethylethyl)2-(phenylMethyl) ester, (S)- | [Molecular Formula]
C17H21NO5 | [MDL Number]
MFCD04115781 | [MOL File]
113400-36-5.mol | [Molecular Weight]
319 |
| Chemical Properties | Back Directory | [Melting point ]
69-70 °C | [Boiling point ]
464.9±38.0 °C(Predicted) | [density ]
1.219 | [storage temp. ]
Sealed in dry,2-8°C | [form ]
Powder | [pka]
-4.32±0.40(Predicted) | [color ]
White | [InChI]
InChI=1S/C17H21NO5/c1-17(2,3)23-16(21)18-13(9-10-14(18)19)15(20)22-11-12-7-5-4-6-8-12/h4-8,13H,9-11H2,1-3H3/t13-/m0/s1 | [InChIKey]
TZNBTMCEMLXYEM-ZDUSSCGKSA-N | [SMILES]
N1(C(OC(C)(C)C)=O)C(=O)CC[C@H]1C(OCC1=CC=CC=C1)=O | [CAS DataBase Reference]
113400-36-5 |
| Hazard Information | Back Directory | [Uses]
Boc-L-pyroglutamic acid benzyl ester is an intermediate in the synthesis of Avibactam, a novel non-beta-lactam β-lactamase inhibitor used in combination with ceftazidime for the treatment of complicated intra-abdominal infections, urinary tract infections, and pneumonia. |
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