| Identification | Back Directory | [Name]
N-cyclopropyl-3-fluoro-4-methyl-5-[3-[[1-[2-[2-(methylamino)ethoxy]phenyl]cyclopropyl]amino]-2-oxo-1(2H)-pyrazinyl]-benzamide | [CAS]
1095004-78-6 | [Synonyms]
AZD-7624
(AZD7624)
AZD-7624; AZD 7624; AZD7624
N-cyclopropyl-3-fluoro-4-methyl-5-[3-[[1-[2-[2-(methylamino)ethoxy]phenyl]cyclopropyl]amino]-2-oxo-1(2H)-pyrazinyl]-benzamide
Benzamide, N-cyclopropyl-3-fluoro-4-methyl-5-[3-[[1-[2-[2-(methylamino)ethoxy]phenyl]cyclopropyl]amino]-2-oxo-1(2H)-pyrazinyl]- | [Molecular Formula]
C27H30FN5O3 | [MDL Number]
MFCD30488989 | [MOL File]
1095004-78-6.mol | [Molecular Weight]
491.56 |
| Chemical Properties | Back Directory | [density ]
1.36±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 250 mg/mL (508.58 mM) | [form ]
Solid | [pka]
13.73±0.20(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
AZD7624 is an inhaled p38 inhibitor, with potent anti-inflammatory activity. | [References]
[1] Pehrson R, et al. AZD7624, an Inhaled p38 Inhibitor, Demonstrates Local Lung Inhibition of LPS-Induced TNFα with Minimal Systemic Exposure. J Pharmacol Exp Ther. 2018 Jun;365(3):567-572. DOI:10.1124/jpet.117.246132 |
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