Hazard Information | Back Directory | [Description]
WF 10129 is a novel angiotensin converting enzyme inhibitor produced by a fungus, Doratomyces putredinis. | [Uses]
WF-10129 is a cytotoxic steroidal compound isolated from the plant Physalis. WF-10129 inhibits liver cancer cell proliferation, induces apoptosis, interferes with metabolism, and significantly reduces lactate production in vitro and in vivo. WF-10129 can also exert anti-tumor activity by regulating the expression of related genes and proteins through the AKT-p53 pathway. | [References]
[1] WF-10129, a novel angiotensin converting enzyme inhibitor produced by a fungus, Doratomyces putredinis |
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