| Identification | Back Directory | [Name]
Ranolazine-d3 | [CAS]
1054624-77-9 | [Synonyms]
RS 43285-d3
Ranolazine-d3
RS 43285-193-d3
N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxy-d3-phenoxy)propyl]-1-piperazineacetamide
N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-[2-(methoxy-d3)phenoxy]propyl]-1-piperazineacetamide | [Molecular Formula]
C24H33N3O4 | [MOL File]
1054624-77-9.mol | [Molecular Weight]
427.537 |
| Chemical Properties | Back Directory | [Appearance]
White Solid | [Melting point ]
113-1160C | [storage temp. ]
-20?C Freezer | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
White | [InChI]
InChI=1S/C24H33N3O4/c1-18-7-6-8-19(2)24(18)25-23(29)16-27-13-11-26(12-14-27)15-20(28)17-31-22-10-5-4-9-21(22)30-3/h4-10,20,28H,11-17H2,1-3H3,(H,25,29) | [InChIKey]
XKLMZUWKNUAPSZ-UHFFFAOYSA-N | [SMILES]
c1cc(OCC(O)CN2CCN(CC(=O)Nc3c(C)cccc3C)CC2)c(OC)cc1 |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
Labeled Ranolazine, intended for use as an internal standard for the quantification of Ranolazine by GC- or LC-mass spectrometry. | [Uses]
Ranolazine is an anti-ischemic agent which modulates myocardial metabolism. Antianginal. | [Physiological effects]
Ranolazine-d3 is the deuterium labeled Ranolazine. Ranolazine (CVT 303) is an anti-angina drug that achieves its effects by inhibiting the late phase of inward sodium current (INa and IKr with IC50 values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP). Ranolazine is also a partial fatty acid oxidation (FAO) inhibitor. |
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