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ChemicalBook--->CAS DataBase List--->1025725-91-0

1025725-91-0

1025725-91-0 Structure

1025725-91-0 Structure
IdentificationBack Directory
[Name]

AVN-101
[CAS]

1025725-91-0
[Synonyms]

AVN-101
AVN-101 (AVN101)
AVN-101 free base
1H-Pyrido[4,3-b]indole, 2,3,4,5-tetrahydro-2,8-dimethyl-5-(2-phenylethyl)-
[Molecular Formula]

C21H24N2
[MOL File]

1025725-91-0.mol
[Molecular Weight]

304.43
Chemical PropertiesBack Directory
[Boiling point ]

480.3±33.0 °C(Predicted)
[density ]

1.10±0.1 g/cm3(Predicted)
[pka]

9.09±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

AVN-101 free base is a multi-target drug candidate with the potential to inhibit central nervous system (CNS) diseases. AVN-101 free base exhibits high inhibitory activity on 5-HT7 receptors and also has certain activity on 5-HT6, 5-HT2A and 5-HT2C receptors. Due to its anxiolytic and antidepressant activities, AVN-101 free base is also expected to be used in diseases such as general anxiety disorder, depression, schizophrenia and multiple sclerosis[1].
[References]

[1] AVN-101: A Multi-Target Drug Candidate for the Treatment of CNS Disorders DOI:10.3233/JAD-151146
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