| Identification | Back Directory | [Name]
1-(4-Chloro-2-nitrophenyl)sulfonyl-4-benzylpiperazine | [CAS]
1024448-59-6 | [Synonyms]
RN 1747
RN-1747 >=98% (HPLC)
1-(4-Chloro-2-nitrophenyl)sulfonyl-4-benzylpiperazine
1-benzyl-4-((4-chloro-2-nitrophenyl)sulfonyl)piperazine
1-(4-Chloro-2-nitrophenyl)sulphonyl-4-benzylpiperazine (RN-1747)
1-[(4-Chloro-2-nitrophenyl)sulfonyl]-4-(phenylmethyl)-piperazine
Piperazine, 1-[(4-chloro-2-nitrophenyl)sulfonyl]-4-(phenylmethyl)- | [Molecular Formula]
C17H18ClN3O4S | [MDL Number]
MFCD04154169 | [MOL File]
1024448-59-6.mol | [Molecular Weight]
395.86 |
| Hazard Information | Back Directory | [Uses]
RN 1747 is a novel TRPV4 modulator. | [Biological Activity]
TRPV4a close relative of the vanilloid receptor TRPV1is activated by diverse modalities such as endogenous lipid ligandshypotonicityprotein kinases andpossiblymechanical inputs. TRPV4 is a nociceptor playing an important role in inflammatory and neuropathic mechanical hyperalgesia in rodent models apparently specifically activated under pathological conditions. | [storage]
+4°C |
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