Identification | Back Directory | [Name]
1 5-DIMETHOXYNAPHTHALENE 97 | [CAS]
10075-63-5 | [Synonyms]
Naphthalene, 1,5-diMethoxy- 1,5-Dimethoxynaphthalene 97% 1 5-DIMETHOXYNAPHTHALENE 97 1,5-DiMethoxynaphthalene | [Molecular Formula]
C12H12O2 | [MDL Number]
MFCD00086779 | [MOL File]
10075-63-5.mol | [Molecular Weight]
188.22 |
Chemical Properties | Back Directory | [Melting point ]
180-184 °C (lit.) | [Boiling point ]
179 °C(Press: 13 Torr) | [density ]
1.097±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [form ]
solid | [Appearance]
Yellow to brown Solid | [InChI]
InChI=1S/C12H12O2/c1-13-11-7-3-6-10-9(11)5-4-8-12(10)14-2/h3-8H,1-2H3 | [InChIKey]
ANCSPRJFGGDREM-UHFFFAOYSA-N | [SMILES]
C1(OC)=C2C(C(OC)=CC=C2)=CC=C1 |
Hazard Information | Back Directory | [Chemical Properties]
Class white crystal | [Synthesis]
Under nitrogen protection, 100 g (0.62 mol) of 1,5-dihydroxynaphthalene (1) was dissolved in 500 mL (1.25 mol) of 10% NaOH solution and the reaction was carried out in a 2 L two-necked round bottom flask. Subsequently, 156 g (1.24 mol) of dimethyl sulfate was slowly added and the addition process lasted for 1 hour. After the reaction was carried out for 2 hours, the resulting precipitate was collected by vacuum filtration. The precipitate was sequentially washed twice with 200 mL of 5% KOH solution and three times with 200 mL of distilled water, followed by drying. The dried residue was completely dissolved in 1.5 L of benzene at 80 °C, which contained 300 g of activated carbon. The hot solution was filtered and left to cool to give 73 g of 1,5-dimethoxynaphthalene as white crystals. The product properties were as follows: yield 63%, melting point 181.9-182.3 °C, Rf value 0.49 [unfolding agent hexane:ethyl acetate (5:1)].1H-NMR (CDCl3, 400 MHz) data: δ 7.70 (d, J = 8.8 Hz, 2H), 7.38 (t, J = 8.0 Hz, 2H), 6.98 (d, J = 8.0 Hz , 2H), 3.94 (s, 6H). | [Purification Methods]
Crystallise it from EtOH, AcOH (m 178-180o) or *C6H6. Also distil it in a vacuum. [Beilstein 6 III 5266, 6 IV 6554.] | [References]
[1] Journal of Chemical Research, 2010, # 9, p. 520 - 521 [2] Israel Journal of Chemistry, 2014, vol. 54, # 5-6, p. 796 - 816 [3] Chemistry - A European Journal, 2015, vol. 21, # 9, p. 3701 - 3707 [4] Angewandte Chemie - International Edition, 2017, vol. 56, # 12, p. 3383 - 3388 [5] Angew. Chem., 2017, vol. 129, # 12, p. 3432 - 3437,6 |
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Energy Chemical
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