| Identification | Back Directory | [Name]
2'-Deoxy-2'-fluoro-beta-D-arabino-2-thiouridine | [CAS]
1006872-85-0 | [Synonyms]
2’-Deoxy-2’-fluoro-β-D-arabino-2-thiouridine
2'-Deoxy-2'-fluoro-b-D-arabino-2-thiouridine
2’-Deoxy-2’-fluoro-beta-D-arabino-2-thiouridine
2'-Deoxy-2'-fluoro-beta-D-arabino-2-thiouridine
4(1H)-Pyrimidinone, 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-2,3-dihydro-2-thioxo- | [Molecular Formula]
C9H11FN2O4S | [MDL Number]
MFCD30748923 | [MOL File]
1006872-85-0.mol | [Molecular Weight]
262.26 |
| Hazard Information | Back Directory | [Uses]
2’-Deoxy-2’-fluoro-β-D-arabino-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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