Identification | Back Directory | [Name]
CAMSTATIN | [CAS]
1002295-95-5 | [Synonyms]
CAMSTATIN L-Serinamide, L-alanyl-L-prolyl-L-α-glutamyl-L-threonyl-L-α-glutamyl-L-arginyl-L-alanyl-L-alanyl-L-valyl-L-alanyl-L-isoleucyl-L-glutaminyl-L-alanyl-L-glutaminyl-L-phenylalanyl-L-arginyl-L-lysyl-L-phenylalanyl-L-glutaminyl-L-lysyl-L-lysyl-L-lysyl-L-alanylglycyl- | [Molecular Formula]
C122H203N39O34 | [MDL Number]
MFCD00792747 | [MOL File]
1002295-95-5.mol | [Molecular Weight]
2760.16 |
Chemical Properties | Back Directory | [storage temp. ]
Desiccate at -20°C | [form ]
Powder | [Water Solubility ]
Soluble to 1 mg/ml in water | [Sequence]
Ala-Pro-Glu-Thr-Glu-Arg-Ala-Ala-Val-Ala-Ile-Gln-Ala-Gln-Phe-Arg-Lys-Phe-Gln-Lys-Lys-Lys-Ala-Gly-Ser-NH2 |
Hazard Information | Back Directory | [Uses]
Camstatin, a functionally active 25-residue fragment of PEP-19's IQ motif, binds calmodulin and inhibits neuronal nitric oxide (NO) synthase[1]. | [IC 50]
nNOS | [References]
[1] J Bradley Dickerson, et al. The influence of phosphorylation on the activity and structure of the neuronal IQ motif protein, PEP-19. Brain Res. 2006 May 30;1092(1):16-27. DOI:10.1016/j.brainres.2006.03.048 |
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